ABSTRACT
Objective To evaluate the effects of acupuncture combined with lifestyle modification for essential hypertension by Meta-analysis. Methods Clinical randomized controlled trial literature about acupuncture combined with lifestyle modification for essential hypertension in CNKI, WanFang Data, CBM, VIP, PubMed, Embase, and Web of Science since establishment to February 20, 2017 were retrieved. Data extraction and quality assessment of studies were conducted by two researchers independently, and the Meta-analysis was performed by the software of RevMan5.3. Results 5 articles involving 467 patients were included. The results of Meta-analysis showed that acupuncture combined with lifestyle modification had more significant effect than lifestyle modification alone in lowing SBP [SMD=-1.52(-2.40,-0.64)], in lowing DBP [SMD=-1.02(-2.01,-0.03)], total effective rates [RR=1.27(1.13, 1.43)]. Conclusion Compared with lifestyle modification alone, acupuncture combined with lifestyle modification have significant effects for patients with essential hypertension, but because of the fewer studies included, bigger heterogeneity between studies and the lower quality of included studies still exist, the results should be further verified, and clinical applications should be treated with caution.
ABSTRACT
Objective To evaluate the dietary arsenic intake level among residents in Hangzhou city,and to provide scientific basis for further food safety assessment.Methods A stratified multi -stage cluster sampling method was performed,and a total of 1 744 subjects were enrolled.Total diet survey was conducted to collect food consumption data through both food -weighting and recording during 3 consecutive days.Representative mixed food samples were prepared for total arsenic (tAs)detecting by using inductively coupled plasma -mass spectrometry (ICP -MS).Daily tAs and weekly presumptive inorganic arsenic (p -inAs)intakes were calculated and compared with corresponding tolerable limit values.Results The medians of dietary tAs and p -inAs intakes were 1 .4 μg/kgbw/d and 3.0 μg/kgbw/week,which accounted for 2.8% and 20.2% of corresponding former TDMI /PTWI,respectively.The tAs and p -inAs intake (1 .6 μg/kg·bw/d and 3.5 μg/kg·bw/week,respectively)in the age group of <1 8 years were significantly higher than that of other age groups (Z =-7.577 ~-2.91 7,P <0.01 ).The mainly source of individual dietary arsenic intakes was cereal foods.Conclusion The dietary intake of tAs and p -inAs are safe,but more attention should be paid to juveniles for the dietary intakes of tAs and p -inAs .